Endocrine Abstracts

Radio-iodine is a safe and effective treatment of thyrotoxicosis, but carries a risk of the late development of hypothyroidism several years after therapy. Patients treated with radio-iodine require long-term follow-up to ensure that late hypothyroidism is detected and treated. Current changes in health care commissioning propose an increasing reliance on primary care for the long term follow-up of patients with thyroid disease. We report a study of the 8 year follow-up of 100...

A 17 year old girl was referred to us from the gynaecology department with history of primary amenorrhea. She was otherwise well and previous medical history included severe acne requiring referral to ENT, plastic surgery and dermatology services at age 13 and hirsutism for which she had privately funded laser treatment. On examination she had acanthosis nigricans and BMI of 22 but was virilised with clitoromegaly, hypertrophied labia majora and hirsuitism. Pelvic ultrasound r...

A 33 year old male presented with a two year history of fatigue, headaches, loss of libido, insomnia, depression and hypertension. On examination, he was floridly Cushingoid with central obesity, proximal muscle weakness and purple striae. A bilateral temporal, superior quadrantanopia was noted on formal perimetry. Investigations revealed markedly elevated prolactin levels at 56560mIU/L, hypogonadotropic hypogonadism and secondary hypothyroidism. He also had elevated urinary c...